Cochrane News
Cochrane Thailand: Bridging gaps and building capacity
Cochrane's strength is in its collaborative, global community. Cochrane Geographic Groups represent Cochrane in their host country, advocate for the use of Cochrane evidence in health policy and practice, and support Cochrane's members and supporters who live there. Here we look more closely at the impact of Cochrane Thailand, exploring its initiatives and contributions to advancing healthcare not only within Thailand but also across the Southeast Asian region.
Since its inception in 2002, initially as the Thai Cochrane Network before evolving into Cochrane Thailand in 2003, the group has been steadfast in its commitment to disseminating the fundamental concepts of research synthesis and championing the importance of evidence-based healthcare. Located at Khon Kaen University in Northeast Thailand, Cochrane Thailand shares information about Cochrane, translates Cochrane plain language summaries into Thai, and provides workshops about preparing Cochrane reviews and how to use the Cochrane related software.
"We are dedicated to promoting the use of Cochrane evidence in healthcare decision-making, with a focus not only on local but also global impact," states Professor Pisake Lumbiganon, Convenor of Cochrane Thailand. "Our designation as the WHO Collaborating Centre for Research Synthesis in Reproductive Health in 2014 and as the WHO HRP Alliance Hub for research capacity strengthening for WHO/SEARO in 2017 underscores our commitment to driving change on a global scale. The reviews we contribute to have a far-reaching impact, with many being incorporated into WHO guidelines. Cochrane Thailand takes pride in its role in shaping healthcare practices both within Thailand and beyond."
One of the group's primary objectives is to facilitate training workshops on Cochrane review preparation and the utilization of related software tools like RevMan and GRADE. These workshops have been instrumental in empowering healthcare researchers across Asia, fostering a community of those equipped with the necessary skills to conduct rigorous research synthesis.
In addition to training initiatives, Cochrane Thailand actively collaborates with various national and international organizations to generate evidence and inform healthcare policies and guidelines. Notably, the group has been invited to support WHO guideline development groups on critical health issues, contributing to the formulation of recommendations that impact healthcare practices globally. Another notable project was working with Cochrane Australia on the five-year 'South East Asia - Optimising Reproductive and Child Health in Developing Countries' project that helped to improve the clinical practice of treating pregnancy and childbirth-related disorders and enhance the health outcomes of mothers and infants in South East Asia.
Cochrane Thailand has also been instrumental in translating Cochrane evidence into Thai, ensuring accessibility for Thai-speaking healthcare professionals, patients and families, and policymakers. With over 1,000 translated Cochrane reviews, the group has significantly enhanced the dissemination and utilization of evidence-based information in the region. "We believe that language should not be a barrier to accessing high-quality healthcare information. Our translation efforts aim to bridge this gap and empower healthcare stakeholders with valuable evidence. We are very proud and thankful to all our volunteer Thai translators who are helping make an impact," emphasizes Nampet Jampathong who helps coordinate the Thai translation.
Looking ahead, Cochrane Thailand is excited about being a Centre of Research Excellence for the project called Accelerating Research and Progress in maternal And Newborn health (ARPAN). This project will help to address the major gaps across the Asia-Pacific region to improve outcomes for women and newborns.
Cochrane Thailand welcomes collaboration and support from individuals and organizations passionate about making a difference in healthcare. they are looking for funding opportunities to continue to expand their impact throughout South Asia. Whether through training workshops, research collaborations, or translation efforts, Cochrane Thailand remains dedicated to its vision of enhancing healthcare practices and policies through rigorous research synthesis and evidence dissemination.
Wednesday, March 13, 2024Massage for neck pain
Global evidence, local impact: broadening participation at the Global Evidence Summit
The second Global Evidence Summit (GES) is taking place in the picturesque city of Prague, Czech Republic, from 10 to 13 September 2024 - registration is still open! Hosted by global leaders in evidence synthesis and evidence-based practice, including Cochrane, JBI, Guidelines International Network (GIN), and The Campbell Collaboration, the summit represents a unique opportunity for knowledge exchange and collaboration. It is an opportunity for professionals across various sectors, such as health, education, social justice, the environment, and climate change, to engage in discussions about producing, summarizing, and disseminating evidence to inform policy and practice.
GES is committed to inclusivity and global partnership, with a particular focus on low- and middle-income countries (LMICs). We spoke with Sabrina Khamissa, Cochrane's Events Support Officer closely involved in GES, to uncover insights, behind-the-scenes information, and updates about the event.
Hi Sabrina! Excitement is building for the upcoming GES event in September. Could you give us an overview of GES's approach to inclusivity and global participation?
Sabrina: The GES stands out as a unique gathering, uniting individuals across various disciplines and roles, from policymakers to patients and government officials to advocates. This diversity is also reflected in our attendees and our program. Ensuring a diverse and representative audience is important to us. Our commitment to including LMICs has been integral to every stage of planning. From the formation of committees working behind the scenes, to the selection of conference themes and speakers, and even to offering discounts to LMIC attendees. We've strived to make the participation of people from LMICs a central focus of the event.
That's wonderful to hear! Could you share a bit about what's happening behind the scenes to involve LMICs that people might not know about?
Sabrina: Absolutely! Behind the scenes, there has been an effort to make the GES accessible and inclusive for participants from LMICs. One aspect that may not be immediately apparent is the meticulous process of selecting the event location. The choice of the Czech Republic was intentional. Its accessibility via train or plane, price points of accommodation and other expenses, and reasonable visa requirements make it an ideal venue that ensures ease and affordability for global attendees. We also have many committees working behind the scenes. We've taken deliberate steps to ensure that these committees encompass a range of perspectives, including representation from LMICs. From reviewing abstract submissions to curating the roster of keynote speakers, diversity is at the forefront of our considerations. This ensures that the program reflects the global diversity of voices and experiences, enriching the summit's discourse and impact.
Registration prices and visa requirements can often pose significant barriers for attendees from LMICs. How is GES addressing these challenges?
Sabrina: To promote inclusivity, we have implemented significantly reduced registration rates for attendees joining us from low-income, lower-middle-income, and upper-middle-income economies, as classified by the World Bank. This initiative aims to mitigate financial barriers that often deter participation from LMICs, ensuring that cost is not a prohibitive factor for delegates seeking to attend GES.
We understand the logistical challenges faced by attendees from LMICs, including visa requirements. To alleviate this burden, we are happy to provide letters of invitation to support visa applications. We encourage all attendees to check visa requirements and if you need a letter, please get in touch as early as possible. Our goal is to facilitate smooth and hassle-free participation for all delegates!
There are also stipends. What exactly are those and what does it cover?
Sabrina: Cochrane is committed to promoting diversity and inclusion within its network and recognizes the importance of making its events accessible to individuals from all backgrounds. The organization understands that individuals from low and middle-income countries may face financial barriers that prevent them from attending GES and wants to help alleviate those barriers by offering stipends and bursaries. This is a long tradition at Cochrane and we have been offering this for many years.
Stipends were made available to those residing in low-, lower-middle-, and upper-middle-income countries who are actively contributing to GES's mission. We are grateful to TDR and EDC TP for sponsoring people from LMICs who may not have otherwise been able to attend. Recipients of these scholarships are expected to provide a report detailing their experiences at the Global Evidence Summit. This report may be utilized as a blog post or news item, contributing to the dissemination of insights and knowledge gained from the event. We also offered stipends for patients and consumers too!
And what about the GES program?
Sabrina: The official GES themes have relevance to LMIC, including sustainable development and global evidence to local impact. Each plenary session will feature an LMIC or UMIC representative speaker, ensuring that diverse perspectives are incorporated into the discussions. Plenaries serve as a valuable platform where all attendees come together for presentations followed by panel discussions—an enriching shared experience for all involved.
The program also encompasses many posters and smaller oral presentations, all revolving around our GES themes. These sessions provide attendees with the opportunity to delve into their specific areas of interest, fostering a dynamic learning environment tailored to individual preferences. As I said before, it's a very unique event and we are confident that there will be interesting content for all attendees!
Looking ahead, what are the long-term implications of efforts in involving LMICs in global initiatives like the Global Evidence Summit?
Sabrina: That's an interesting question and it's been one that we have been conscious of. GES organizers and the partners involved truly feel that the efforts extend far beyond the confines of a GES single event. By fostering collaboration and knowledge exchange among diverse people, we lay the foundation for sustainable partnerships that transcend geographical boundaries. Ultimately, we aim to empower attendees to take ownership of evidence-based practices, driving positive health outcomes and equity on a global scale.
Registration is still open for GES (with onsite registration available!) and we're looking forward to welcoming you all to Prague! See you there!
Cochrane seeks Data Scientist (UK remote – flexible)
Specifications: 6-Months Fixed –Term Contract
Salary: Hourly Rate – £12-£15 per Hour depending on experience
(Please note: This is a short-term project-based contract that is open to anyone who would like to gain experience in this field without necessarily having professional experience.)
Location: UK (Remote – Flexible)
Closing date: 11 March 2024
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
As Cochrane’s Data Scientist, you will work with our technology, product and publishing teams to leverage data in supporting the work of Cochrane in advocating for evidence-informed health decision-making worldwide.
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.
Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.
You can expect:
- An opportunity to truly impact health globally.
- A flexible work environment
- A comprehensive onboarding experiences.
- An environment where people feel welcome, heard, and included, regardless of their differences.
Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.
How to apply
- For further information on the role and how to apply
- The deadline to receive your application is 11th March, 2024.
- The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
- Read our Recruitment Privacy Statement
Cochrane seeks FES Implementation Officer (UK, remote – flexible)
Specifications: 1-Year Fixed Term Contract
Salary: £35,000 per Annum
Location: UK (Remote – Flexible)
Closing date: 15 March 2024
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
The Future of Evidence Synthesis (FES) is a critical programme of work for Cochrane over the next 3 years. Successful delivery is essential for Cochrane’s future and sustainability. A core component of the new production model is the creation of Cochrane Evidence Synthesis Units and Thematic Groups. This role will work closely with the Head of Change Management, to support the Thematic Groups and Evidence Synthesis Units across the implementation cycle – from application process management, through to onboarding and monitoring and evaluation.
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.
Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.
You can expect:
- An opportunity to truly impact health globally.
- A flexible work environment
- A comprehensive onboarding experiences.
- An environment where people feel welcome, heard, and included, regardless of their differences.
Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.
How to apply
- For further information on the role and how to apply
- The deadline to receive your application is 15 March 2024.
- The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
- Read our Recruitment Privacy Statement
How effective and safe are single-incision slings for women with urinary incontinence compared with other operations?
Cochrane examines the evidence base for the effectiveness and implementation of Hospital at Home programmes
A new Cochrane Library Editorial has been released following the publication of two Cochrane systematic reviews on Hospital at Home (HAH) programmes, urging a shift in the trajectory of HaH research.
Hospital at Home provides hospital-level care at home, for people who would otherwise be inpatients in hospital. One type of Hospital at Home is to avoid admission to hospital. This is called Admission Avoidance Hospital at Home. These services replace an admission to hospital, for people whose condition would normally need treatment in a hospital bed, for example for a flare-up of a lung condition. Instead, a doctor can refer a patient they assess as being suitable to receive treatment for an illness in their own home (or the place where they usually live, including in residential care), for a limited time. Another type is called Early Discharge Hospital at Home. These services shorten the length of time people need to stay in hospital after being admitted as an inpatient, for example following surgery or treatment for an illness or condition. The care patients would usually receive from healthcare professionals in a hospital bed is instead provided in their home, and is not expected to compromise the quality of care.
This first Cochrane review examined if providing health care in an admission avoidance hospital at home setting improves patient health outcomes and reduces health service costs.
Edgar K, Iliffe S, Doll HA, Clarke MJ, Gonçalves-Bradley DC, Wong E, Shepperd S. Admission avoidance hospital at home. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: CD007491. DOI: 10.1002/14651858.CD007491.pub3.
The second Cochrane review is a qualitative evidence synthesis on what is important when introducing, running, and receiving care from Hospital at Home services. The authors wanted to explore a range of experiences of, and views on, Admission Avoidance and Early Discharge services. Topics covered things that managers want to know when planning to set up a Hospital at Home service, healthcare professionals’ views on working in a Hospital at Home service, what matters to patients who receive this type of care, or how family and caregivers experience Hospital at Home services for those they care for.
Wallis JA, Shepperd S, Makela P, Han JX, Tripp EM, Gearon E, Disher G, Buchbinder R, O'Connor D. Factors influencing the implementation of early discharge hospital at home and admission avoidance hospital at home: a qualitative evidence synthesis. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: CD014765. DOI: 10.1002/14651858.CD014765.pub2.
These two updated Cochrane reviews demonstrate HaH's clinical and cost-effectiveness but also show the lack of effective scale-up strategies. An accompanying Cochrane Library editorial strongly suggests that the future direction of HaH research must move beyond repeating clinical and cost-effectiveness studies comparing HaH to usual care and instead focus on identifying and testing strategies to increase adoption and sustainability across different healthcare systems.
The authors summarized the Cochrane Library Editorial by saying:
Key challenges that needs to be addressed are: patient and caregiver engagement, policy development, and sustainability to integrate HaH as a core component of acute care strtagies.
Lai YF, Ko SQ. Time to shift the research agenda for Hospital at Home from effectiveness to implementation. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: ED000165. DOI: 10.1002/14651858.ED000165.
Tuesday, March 5, 2024Smartphone apps for people with overweight or obesity
Cochrane seeks Product Manager (permanent, UK remote)
Specifications: Permanent – Full Time
Salary: £40,000 per Annum
Location: UK (Remote) with occasional travel to London Office
Closing date: 7 March 2024
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
You will manage the product roadmap and product lifecycle for commercial products, primarily focusing on the development of premium product offerings which leverage Cochrane evidence and content.
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.
Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.
You can expect:
- An opportunity to truly impact health globally.
- A flexible work environment
- A comprehensive onboarding experiences.
- An environment where people feel welcome, heard, and included, regardless of their differences.
Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.
How to apply
- For further information on the role and how to apply, please click here
- The deadline to receive your application is 07 March, 2024.
- The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
- Read our Recruitment Privacy Statement
Cerebrolysin for acute ischaemic stroke
Does meditation help prevent people from developing cardiovascular disease or from worsening cardiovascular disease?
Cochrane seeks Governance Officer (permanent, remote UK)
Specifications: Permanent – Full Time
Salary: £31,000 per Annum
Location: UK (Remote with occasional travel to the London office)
Directorate: CEOO
Closing date: 05 March 2024
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
The Governance Officer works at the most senior level in the organisation, ensuring the smooth running of Cochrane’s governance function and the systems and processes that support it.
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.
Our organization is built on four core values:
Collaboration: Underpins everything we do, locally and globally.
Relevant: The right evidence at the right time in the right format.
Integrity: Independent and transparent.
Quality: Reviewing and improving what we do, maintaining rigour and trust.
You can expect:
- An opportunity to truly impact health globally.
- A flexible work environment
- A comprehensive onboarding experiences.
- An environment where people feel welcome, heard, and included, regardless of their differences.
Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.
How to apply
- For further information on the role and how to apply
- The deadline to receive your application is 5th March, 2024.
- The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
- Read our Recruitment Privacy Statement
Cochrane Sweden wrongly suspended from social media platform X
Last week, a report co-authored by Cochrane Sweden revealed that the results of hundreds of Nordic clinical trials remain unpublished. The team shared the report on the social media platform X, formerly known as Twitter. Two days later, their account was suspended from the platform following reports from unknown users. The team are appealing the decision but have had no response so far.
Since 2019, Cochrane Sweden have been involved in improving trial transparency, publishing reports and organizing international webinars. The latest report found that 475 clinical trials involving 83,903 patients completed during 2016-19 in Denmark, Iceland, Finland, Norway and Sweden have never made their results public in any form.
“We shared the report on Nordic trial transparency on Tuesday 6 February, and by Thursday our Cochrane Sweden X account was suspended unexpectedly,” says Matteo Bruschettini, Director of Cochrane Sweden and co-author of the report. “We have initiated an appeal against the suspension, which is apparently for ‘pretending to be another entity in a misleading or deceptive manner’. We suspect that we were reported maliciously in response to our latest report, which is extremely unfortunate. We are currently considering whether to dismiss X and focus on other social media channels.”
X’s rules on ‘platform integrity and authenticity’ state that accounts will be suspended if they are ‘engaged in impersonation or are using a deceptive identity’. This is clearly not the case for Cochrane Sweden’s X account, which has always been run by Cochrane Sweden.
This is not the first time that Cochrane-affiliated social media channels have been erroneously censored by social media platforms. During the COVID-19 pandemic, Cochrane social media posts sharing evidence that ivermectin and hydroxychloroquine were ineffective treatments were removed from various social media platforms and wrongly tagged as ‘misinformation’.
“It’s disturbing to see that social media rules aimed at preventing misinformation are being used to do the exact opposite,” says Catherine Spencer, Chief Executive of the Cochrane Collaboration. “Social media platforms must do more to protect trusted sources from vexatious or malicious reports, and act swiftly to correct things when they make a mistake. Cochrane Sweden’s important work to promote research integrity has been undermined by rules ostensibly aimed at safeguarding integrity and authenticity. We stand behind Cochrane Sweden and urge X to restore their account as soon as possible.”
Cochrane launches new Interactive Learning module on qualitative evidence synthesis
This introductory module teaches participants how to systematically combine and analyze evidence from individual qualitative studies. The module, designed to be completed in about 90 minutes, aims to provide participants with a solid foundation in framing a QES question, scoping a topic, assessing available evidence, synthesizing data, and proficiently presenting findings in a comprehensive report.
Professor Jane Noyes, one of the module's authors, says "This module aims to provide learners with a basic overview of designing and conducting a QES. We prioritized the key methods and stages in the design and conduct of a qualitative evidence synthesis."
QES has emerged as a crucial approach for informing guideline development and addressing implementation considerations in diverse country settings and complex health systems.
"We're dedicated to meeting the needs of our end-users by diversifying the evidence we offer in the Cochrane Library. Embracing qualitative evidence synthesis strengthens our capacity to fulfill these needs. I'm thankful for the dedication of the Methods QES Group, whose efforts-from the groundbreaking Cochrane Interactive Learning to the influential Cochrane-Campbell Handbook-advance the dissemination of qualitative evidence synthesis, fostering a future where every voice is valued," Karla Soares-Weiser, Editor in Chief of the Cochrane Library, says.
Developed by the Cochrane Qualitative and Implementation Methods Group in collaboration with the Learning Team in Cochrane's Development Directorate, the twelfth module reflects dedication to delivering high-quality, engaging, and innovative distance learning experiences.
The module includes links to relevant chapters from the Cochrane-Campbell Handbook for Qualitative Evidence Synthesis, allowing learners to access more detailed methods guidance for those seeking in-depth information.
Andrew Booth, who also authored the module, shares his excitement: "Having spent over a decade delivering face-to-face training events on qualitative evidence synthesis, it was really exciting to be steered towards explaining the same concepts and techniques for an international online community."
Notably, certain Cochrane contributors and residents of HINARI countries may access the new module and the entire Cochrane Interactive Learning course free of charge. Additionally, subscription options are available for both individuals and institutions interested in accessing this valuable resource. For further details and to access the new module, please visit the Cochrane Interactive Learning page.
May Silveira Bianchim, a Cochrane Qualitative and Implementation Methods Group (QIMG) intern, underscores the value of the introductory module in her professional development: "As a Cochrane QMIG intern, the introductory module is an invaluable resource for learning the basic steps of qualitative evidence synthesis, providing insights that are instrumental in applying this knowledge to practice. This experience has been meaningful to my ongoing professional development."
Friday, February 16, 2024Use of red flags to screen for vertebral fractures in people with low back pain
Hundreds of Nordic clinical trials remain unpublished
A new report jointly published by the AllTrials campaign, Cochrane Denmark, Cochrane Norway, Cochrane Sweden, the Dam Foundation, Melanomföreningen, and TranspariMED found that 475 clinical trials involving 83,903 patients completed during 2016-19 in Denmark, Iceland, Finland, Norway and Sweden have never made their results public in any form. This accounted for 22% of all clinical trial results across the five countries.
In cases where clinical trial results were made public, there was often a delay in publication. The report found that only 27% of all trials results were made public, in either registries or in journals, within 12 months. Within two years of study completion, only around half of the results were available to the public.
Not only is this lack of transparency in clinical trials a waste of increasingly scarce public funding, it harms patients and leaves gaps in medical evidence. This makes it very difficult to determine how safe and effective treatments actually are.
Nordic countries have recently changed regulations that require institutions to make the results of drug and device trials public on registries within 12 months of completion. While clinical trials which ended in the years prior to 2023 are not included in this legislation, both the Declaration of Helsinki and World Health Organization have clearly stated for years that the timely public sharing of results is an ethical obligation.
Matteo Bruschettini, Director of Cochrane Sweden, who co-authored the report, said: “At Cochrane we highly value that findings of all studies become available. Otherwise, the synthesis of the evidence misses information thus resulting in misleading conclusions. This ultimately impacts the patients, clinicians and policy makers who need to make decisions based on a distorted picture of the evidence. This report should encourage initiatives to deal with this issue of medical research waste in the Nordic countries.”
The report calls for policy makers in Denmark, Iceland, Finland, Norway and Sweden to adopt national legislation requiring that the results of all clinical trials are made public and to set up monitoring mechanisms. It also calls for national medicines regulators and research funders to put in structures to prevent research waste and ensure that clinical trial results are made public. This is in line with WHO recommendations which urged ethics committees, regulatory authorities, professional bodies, sponsors, investigators, and funding agencies to act in their jurisdictions to ensure results from all clinical trials are reported and publicly disclosed.
The report has already received attention in Swedish media.
Cochrane will continue to advocate for improved clinical trial transparency, and will monitor progress in these countries with interest.
Thursday, February 8, 2024Cochrane seeks Geographic Groups/Program Manager
Specifications: Permanent – Full Time
Salary: £42,000 per Annum
Location: (Remote – Flexible) UK, Germany, Denmark. Candidates anywhere from the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: CEOO
Closing date: 18 February 2024
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
As a Manager within Cochrane’s Central Executive Team, you will support Cochrane’s Geographic Groups, Networks, and Fields, play a pivotal role in supporting sustainable development, coordinating activities, and enhancing accountability frameworks. This position focuses on fostering collaboration, overseeing communication, and promoting growth within Cochrane’s global networks.
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.
Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.
You can expect:
- An opportunity to truly impact health globally.
- A flexible work environment
- A comprehensive onboarding experiences.
- An environment where people feel welcome, heard, and included, regardless of their differences.
Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.
How to apply
- For further information on the role and how to apply,
- The deadline to receive your application is 18th Feb, 2024.
- The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
- Read our Recruitment Privacy Statement